The interplay between cationic peptide sequence, siRNA and electrolyte: formulating lipopolyplexes in NaCl solution affords nanocomplexes with exceptional levels of gene silencing

Lipopolyplexes are important non-viral vectors for the delivery of therapeutic siRNA. However, many formulations developed are unstable or show poor cellular uptake under physiologically relevant conditions, for example in the presence of serum. In this work, we have studied the effects of formulati...

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Manylion Llyfryddiaeth

Prif Awduron:	Lili Cui, Laila Kudsiova, Frederick Campbell, David J. Barlow, Ann E. Terry, Yining Ma, Najet Mahmoudi, Helen C. Hailes, Alethea B. Tabor, M. Jayne Lawrence
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	The Royal Society of Chemistry 2026-06-01
Cyfres:	RSC Pharmaceutics
Mynediad Ar-lein:	https://pubs.rsc.org/pm/article-pdf/doi/10.1039/d6pm00042h/13158725/d6pm00042h.pdf
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