The interplay between cationic peptide sequence, siRNA and electrolyte: formulating lipopolyplexes in NaCl solution affords nanocomplexes with exceptional levels of gene silencing
Lipopolyplexes are important non-viral vectors for the delivery of therapeutic siRNA. However, many formulations developed are unstable or show poor cellular uptake under physiologically relevant conditions, for example in the presence of serum. In this work, we have studied the effects of formulati...
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| Autori principali: | , , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Royal Society of Chemistry
2026-06-01
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| Serie: | RSC Pharmaceutics |
| Accesso online: | https://pubs.rsc.org/pm/article-pdf/doi/10.1039/d6pm00042h/13158725/d6pm00042h.pdf |
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