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Doxorubicin-conjugated siRNA lipid nanoparticles for combination cancer therapy

Evasion of apoptosis is a hallmark of cancer, attributed in part to overexpression of the anti-apoptotic protein B-cell lymphoma 2 (Bcl-2). In a variety of cancer types, including lymphoma, Bcl-2 is overexpressed. Therapeutic targeting of Bcl-2 has demonstrated efficacy in the clinic and is the subj...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Kamila Butowska, Xuexiang Han, Ningqiang Gong, Rakan El-Mayta, Rebecca M. Haley, Lulu Xue, Wenqun Zhong, Wei Guo, Karin Wang, Michael J. Mitchell
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2023-04-01
Sarja:Acta Pharmaceutica Sinica B
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Linkit:http://www.sciencedirect.com/science/article/pii/S2211383522003239
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