Performance of Pyridylthiourea‐Polyethylenimine Polyplex for siRNA‐Mediated Liver Cancer Therapy in Cell Monolayer, Spheroid, and Tumor Xenograft Models

Medical application of siRNAs relies on methods for delivering nucleic acids into the cytosol. Synthetic carriers, which assemble with nucleic acids into delivery systems, show promises for cancer therapy but efficiency remains to be improved. In here, the effectiveness of pyridylthiourea‐polyethyle...

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Detalhes bibliográficos

Principais autores:	Jean Baptiste Gossart, Etienne Pascal, Florent Meyer, Emilie Heuillard, Mathieu Gonçalves, Francine Gossé, Eric Robinet, Benoît Frisch, Cendrine Seguin, Guy Zuber
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2017-07-01
coleção:	Global Challenges
Assuntos:	delivery system liver cancer polo‐like kinase polyethylenimine siRNA
Acesso em linha:	https://doi.org/10.1002/gch2.201700013
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