Molecular design, functional characterization and structural basis of a protein inhibitor against the HIV-1 pathogenicity factor Nef.
Increased spread of HIV-1 and rapid emergence of drug resistance warrants development of novel antiviral strategies. Nef, a critical viral pathogenicity factor that interacts with host cell factors but lacks enzymatic activity, is not targeted by current antiviral measures. Here we inhibit Nef funct...
Збережено в:
| Автори: | , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Public Library of Science (PLoS)
2011-01-01
|
| Серія: | PLoS ONE |
| Онлайн доступ: | https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625496/pdf/?tool=EBI |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|