Temperature and WNK-SPAK/OSR1 Kinases Dynamically Regulate Antiviral Human GFP-MxA Biomolecular Condensates in Oral Cancer Cells

Phase-separated membraneless biomolecular condensates in the cytoplasm and nucleus are now recognized to play a major role in modulating diverse functions in mammalian cells, and contribute to cancer pathogenesis through dysregulated function of condensates of transcription factors such as STAT3 and...

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Autori principali:	Pravin B. Sehgal, Huijuan Yuan, Susan V. DiSenso-Browne
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2025-06-01
Serie:	Cells
Soggetti:	pathogenesis of oral cancer anatomical sites of oral cancer hypotonic and temperature stresses structure of biomolecular condensates human myxovirus resistance protein (MxA/Mx1) WNK-SPAK/OSR1 kinases
Accesso online:	https://www.mdpi.com/2073-4409/14/13/947
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