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In Vitro Evaluation of the Antiviral Properties of Exogenous mRNA Encoding the Human MxA Protein

MxA is a cytoplasmic protein induced in human cells exposed to type I and III interferons. It can inhibit various viruses, including influenza A, by blocking the early steps of the viral replication cycle. The rapid advancement of mRNA-based technology has allowed us to evaluate the antiviral activi...

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Principais autores: Marina A. Plotnikova, Ekaterina A. Romanovskaya-Romanko, Anastasia A. Pulkina, Marina A. Shuklina, Anna-Polina S. Shurygina, Sergey A. Klotchenko
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-01-01
Serier:Microbiology Research
Fag:
exogenous mRNA
MxA
antiviral activity
Online adgang:https://www.mdpi.com/2036-7481/16/2/32
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