Growth-coupled selection of 5-aminolevulinic acid synthetase mutants for 5-aminolevulinic acid biosynthesis in Corynebacterium glutamicum

Introduction5-Aminolevulinic acid (5-ALA) is a nonprotein amino acid with broad applications in agriculture, medicine, and the food industry. In recent years, substantial efforts have been devoted to enhancing its biosynthesis. The catalytic activity of 5-aminolevulinic acid synthase (ALAS) is a cri...

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Bibliografische Detailangaben

Hauptverfasser:	Peng Yang, Yutian Fan, Yajuan Zhao, Yan Yu, Xinping Yan, Lu Han, Xinqiang Song, An-dong Gong
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-11-01
Schriftenreihe:	Frontiers in Microbiology
Schlagworte:	5-aminolevulinic acid 5-aminolevulinic acid synthetase growth-coupled selection fermentation optimization biosynthesis
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fmicb.2025.1717625/full
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