The cytoskeleton dynamics-dependent LINC complex in periodontal ligament stem cells transmits mechanical stress to the nuclear envelope and promotes YAP nuclear translocation

Abstract Background Periodontal ligament stem cells (PDLSCs) are important seed cells in tissue engineering and clinical applications. They are the priority receptor cells for sensing various mechanical stresses. Yes-associated protein (YAP) is a recognized mechanically sensitive transcription facto...

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Egile Nagusiak:	Xuehuan Meng, Ye Zhu, Hao Tan, Baraa Daraqel, Ye Ming, Xiang Li, Guoyin Yang, Xinyi He, Jinlin Song, Leilei Zheng
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	BMC 2024-09-01
Saila:	Stem Cell Research & Therapy
Gaiak:	Cytoskeleton LINC complex Mechanotransduction Proliferation Tissue remodeling YAP
Sarrera elektronikoa:	https://doi.org/10.1186/s13287-024-03884-0
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!