Reporting and communication of sample size calculations in adaptive clinical trials: a review of trial protocols and grant applications
Abstract Background An adaptive design allows modifying the design based on accumulated data while maintaining trial validity and integrity. The final sample size may be unknown when designing an adaptive trial. It is therefore important to consider what sample size is used in the planning of the st...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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BMC
2024-09-01
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| Serie: | BMC Medical Research Methodology |
| Soggetti: | |
| Accesso online: | https://doi.org/10.1186/s12874-024-02339-7 |
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