Effect of Antihypertensive Losartan on Ca²⁺ Mobilization in the Aorta of Middle-Aged Spontaneously Hypertensive Female Rats

Hypertension, a leading factor for cardiovascular diseases (CVD), is a particularly heavy burden in women during middle age, when cardioprotective hormones begin to decline. The abnormal handling of calcium (Ca²⁺) in vascular smooth muscle cells (VSMCs) leads to increased vasoconstriction...

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Bibliografiske detaljer

Principais autores:	Swasti Rastogi, Jessica Liaw, Yingnan Zhai, Tatiana Karpova, Linxia Gu, Kenia Nunes
Format:	Artigo
Sprog:	Inglês
Udgivet:	MDPI AG 2025-11-01
Serier:	Journal of Cardiovascular Development and Disease
Fag:	hypertension vascular dysfunction Ca<sup>2+</sup> mishandling middle-aged female losartan aortic stiffness
Online adgang:	https://www.mdpi.com/2308-3425/12/11/441
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