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Development of nanobodies targeting hepatocellular carcinoma and application of nanobody-based CAR-T technology

Abstract Background Chimeric antigen receptor T (CAR-T) cell therapy, as an emerging anti-tumor treatment, has garnered extensive attention in the study of targeted therapy of multiple tumor-associated antigens in hepatocellular carcinoma (HCC). However, the suppressive microenvironment and individu...

Ful tanımlama

Kaydedildi:
Asıl Yazarlar: Keming Lin, Baijin Xia, Xuemei Wang, Xin He, Mo Zhou, Yingtong Lin, Yidan Qiao, Rong Li, Qier Chen, Yuzhuang Li, Jinzhu Feng, Tao Chen, Cancan Chen, Xinyu Li, Hui Zhang, Lijuan Lu, Bingfeng Liu, Xu Zhang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BMC 2024-04-01
Seri Bilgileri:Journal of Translational Medicine
Konular:
HCC
Nanoparticle
Nanobody
Phage display
Nb-derived CAR-T cell therapy
Online Erişim:https://doi.org/10.1186/s12967-024-05159-x
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