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Intracellular autofluorescence enables the isolation of viable, functional human muscle reserve cells with distinct Pax7 levels and stem cell states

Abstract Background Human muscle reserve cells (MuRC) represent a quiescent MuSC population generated in vitro that exhibit heterogeneous Pax7 expression, with a Pax7High subset in a deeper quiescent state. However, the conventional method of identifying Pax7High cells involves intracellular stainin...

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Autors principals: Axelle Bouche, Diego Michel, Perrine Castets, Didier Hannouche, Thomas Laumonier
Format: Artigo
Idioma:Inglês
Publicat: BMC 2025-12-01
Col·lecció:Stem Cell Research & Therapy
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Accés en línia:https://doi.org/10.1186/s13287-025-04811-7
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