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Arginine catabolism is essential to polymyxin dependence in Acinetobacter baumannii

Summary: Polymyxins are often the only effective antibiotics against the “Critical” pathogen Acinetobacter baumannii. Worryingly, highly polymyxin-resistant A. baumannii displaying dependence on polymyxins has emerged in the clinic, leading to diagnosis and treatment failures. Here, we report that a...

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Sparad:
Huvudupphov: Mei-Ling Han, Yasser Alsaadi, Jinxin Zhao, Yan Zhu, Jing Lu, Xukai Jiang, Wendong Ma, Nitin A. Patil, Rhys A. Dunstan, Anton P. Le Brun, Hasini Wickremasinghe, Xiaohan Hu, Yimin Wu, Heidi H. Yu, Jiping Wang, Christopher K. Barlow, Phillip J. Bergen, Hsin-Hui Shen, Trevor Lithgow, Darren J. Creek, Tony Velkov, Jian Li
Materialtyp: Artigo
Språk:Inglês
Utgiven: Elsevier 2024-07-01
Serie:Cell Reports
Ämnen:
CP: Microbiology
CP: Metabolism
Länkar:http://www.sciencedirect.com/science/article/pii/S2211124724007393
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