Practical High-Throughput Method to Screen Compounds for Anthelmintic Activity against <i>Caenorhabditis elegans</i>

In the present study, we established a practical and cost-effective high throughput screening assay, which relies on the measurement of the motility of <i>Caenorhabditis elegans</i> by infrared light-interference. Using this assay, we screened 14,400 small molecules from the “HitFinder” library (May...

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Autori principali:	Aya C. Taki, Joseph J. Byrne, Peter R. Boag, Abdul Jabbar, Robin B. Gasser
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-07-01
Serie:	Molecules
Soggetti:	high throughput screening <i>Caenorhabditis elegans</i> phenotypic screen motility infrared light-interference anthelmintic
Accesso online:	https://www.mdpi.com/1420-3049/26/14/4156
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