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Genome-wide reconstruction of the intrinsic apoptosis pathway in Haemonchus contortus

Abstract Background Programmed cell death (or apoptosis) is a fundamental process in metazoans, extensively characterised in mammals and other vertebrates but much less so in invertebrates beyond the free-living nematode Caenorhabditis elegans and the vinegar fly – Drosophila melanogaster. Here, we...

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Principais autores: Yanxiang Shen, Neil D. Young, Jiangning Song, Brad E. Sleebs, Bill C. H. Chang, Erinna F. Lee, Walter D. Fairlie, Robin B. Gasser
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-02-01
Serier:BMC Genomics
Fag:
Haemonchus contortus
Nematode
Apoptosis
Intrinsic pathway
Structural modelling
Post-transcriptional regulation
Online adgang:https://doi.org/10.1186/s12864-026-12596-z
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