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Structural Diversity of Neuronal Calcium Sensor Proteins and Insights for Activation of Retinal Guanylyl Cyclase by GCAP1

Neuronal calcium sensor (NCS) proteins, a sub-branch of the calmodulin superfamily, are expressed in the brain and retina where they transduce calcium signals and are genetically linked to degenerative diseases. The amino acid sequences of NCS proteins are highly conserved but their physiological fu...

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Autori principali: Sunghyuk eLim, Alexander eDizhoor, James eAmes
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2014-03-01
Serie:Frontiers in Molecular Neuroscience
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Accesso online:http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00019/full
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