Structural Diversity of Neuronal Calcium Sensor Proteins and Insights for Activation of Retinal Guanylyl Cyclase by GCAP1

Neuronal calcium sensor (NCS) proteins, a sub-branch of the calmodulin superfamily, are expressed in the brain and retina where they transduce calcium signals and are genetically linked to degenerative diseases. The amino acid sequences of NCS proteins are highly conserved but their physiological fu...

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Hlavní autoři:	Sunghyuk eLim, Alexander eDizhoor, James eAmes
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2014-03-01
Edice:	Frontiers in Molecular Neuroscience
Témata:	Calcium Recoverin NMR Ca2+-myristoyl switch EF-hand GCAP1
On-line přístup:	http://journal.frontiersin.org/Journal/10.3389/fnmol.2014.00019/full
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