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Unveiling DNAJB12 and DNAJB14 as crucial chaperones in hepatitis B and D virus particle morphogenesis

Summary: During chronic HBV infection, the massive secretion of HBV envelope proteins (HBsAg) as non-infectious subviral particles (SVPs) remains a significant challenge in achieving a functional cure. Despite this, the HBsAg folding process, essential for HBV and HDV particle morphogenesis, remains...

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Bibliografische gegevens
Hoofdauteurs: Léna Angelo, Richard Boulon, Patrick Labonté
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2026-02-01
Reeks:iScience
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Online toegang:http://www.sciencedirect.com/science/article/pii/S2589004225021583
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