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Pharmacological Inhibition and Genetic Knockdown of BCL9 Modulate the Cellular Landscape of Cancer-Associated Fibroblasts in the Tumor-Immune Microenvironment of Colorectal Cancer

Cancer-associated fibroblasts (CAFs) exert a key role in cancer progression and liver metastasis. They are activated in the tumor microenvironment (TME), but their prometastatic mechanisms are not defined. CAFs are abundant in colorectal cancer (CRC). However, it is not clear whether they are raised...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Mengxuan Yang, Zhuang Wei, Mei Feng, Yuanyuan Zhu, Yong Chen, Di Zhu
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Frontiers Media S.A. 2021-05-01
Цуврал:Frontiers in Oncology
Нөхцлүүд:
Онлайн хандалт:https://www.frontiersin.org/articles/10.3389/fonc.2021.603556/full
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