Inhibition of DPP-4 Attenuates Endotoxemia-Induced NLRC4 Inflammasome and Inflammation in Visceral Adipose Tissue of Mice Fed a High-Fat Diet

Inflammasomes are protein complexes that trigger pro-inflammatory responses and promote many diseases, including adipose tissue dysfunction. Linagliptin (L), a DPP-4 inhibitor used for type 2 diabetes therapy, has putative anti-inflammatory effects. This work explores L effects on inflammasome regul...

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Detalhes bibliográficos

Principais autores:	Francesca Bianchi, Paola Roccabianca, Elena Vianello, Guendalina Gentile, Lucia La Sala, Francesco Bandera, Lorenza Tacchini, Riccardo Zoia, Massimiliano M. Corsi Romanelli, Elena Dozio
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-02-01
coleção:	Biomolecules
Assuntos:	adipocytes DPP-4 endotoxemia fat high-fat diet inflammation
Acesso em linha:	https://www.mdpi.com/2218-273X/15/3/333
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