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Dynamics of oxylipin biosynthesis in systemic inflammation: insights from a large animal model of endotoxemia

IntroductionEndotoxemia, marked by the presence of bacterial lipopolysaccharide (LPS) in the bloodstream, induces acute inflammation and is implicated in both mortality and chronic disease across species. LPS stimulates lipolysis and activates cyclooxygenase (COX), lipoxygenase (LOX), and cytochrome...

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Bibliografski detalji
Glavni autori: Madison N. Myers, Miguel Chirivi, Jose M. dos Santos Neto, Jair Parales-Girón, Lynn C. Worden, Adam L. Lock, G. Andres Contreras
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2025-06-01
Serija:Frontiers in Immunology
Teme:
Online pristup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1595888/full
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