A single-cell atlas of normal and KRASG12D-malformed lymphatic vessels

Somatic activating mutations in KRAS can cause complex lymphatic anomalies (CLAs). However, the specific processes that drive KRAS-mediated CLAs have yet to be fully elucidated. Here, we used single-cell RNA sequencing to construct an atlas of normal and KrasG12D-malformed lymphatic vessels. We iden...

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Detalles Bibliográficos

Principais autores:	Lorenzo M. Fernandes, Danielle Griswold-Wheeler, Jeffrey D. Tresemer, Angelica Vallejo, Neda Vishlaghi, Benjamin Levi, Abigail Shapiro, Joshua P. Scallan, Michael T. Dellinger
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical investigation 2025-03-01
Series:	JCI Insight
Assuntos:	Angiogenesis Development Vascular biology
Acceso en liña:	https://doi.org/10.1172/jci.insight.185181
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