Synaptic biomarkers in the cerebrospinal fluid associate differentially with classical neuronal biomarkers in patients with Alzheimer’s disease and frontotemporal dementia

Abstract Background Loss of synaptic functionality has been recently identified as an early-stage indicator of neurological diseases. Consequently, monitoring changes in synaptic protein levels may be relevant for observing disease evolution or treatment responses in patients. Here, we have studied...

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Principais autores:	Shreyasee Das, Julie Goossens, Dirk Jacobs, Nele Dewit, Yolande A. L. Pijnenburg, Sjors G. J. G. In ‘t Veld, Charlotte E. Teunissen, Eugeen Vanmechelen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2023-03-01
coleção:	Alzheimer’s Research & Therapy
Assuntos:	Biomarkers Immunoassay Synapse Dementia Alzheimer’s disease Frontotemporal dementia
Acesso em linha:	https://doi.org/10.1186/s13195-023-01212-x
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