CSF synaptic protein concentrations are raised in those with atypical Alzheimer’s disease but not frontotemporal dementia

Abstract Background Increased CSF levels of a number of synaptic markers have been reported in Alzheimer’s disease (AD), but little is known about their concentrations in frontotemporal dementia (FTD). We investigated this in three synaptic proteins, neurogranin, SNAP-25, and synaptotagmin-1. Method...

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Hlavní autoři:	Mica T. M. Clarke, Ann Brinkmalm, Martha S. Foiani, Ione O. C. Woollacott, Carolin Heller, Amanda Heslegrave, Ashvini Keshavan, Nick C. Fox, Jonathan M. Schott, Jason D. Warren, Kaj Blennow, Henrik Zetterberg, Jonathan D. Rohrer
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2019-12-01
Edice:	Alzheimer’s Research & Therapy
Témata:	Alzheimer’s disease Frontotemporal dementia Synaptic Biomarkers Neurogranin SNAP-25
On-line přístup:	https://doi.org/10.1186/s13195-019-0564-2
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