Role of the hydrophobic and charged residues in the 218–226 region of apoA-I in the biogenesis of HDL1[S]

We investigated the significance of hydrophobic and charged residues 218–226 on the structure and functions of apoA-I and their contribution to the biogenesis of HDL. Adenovirus-mediated gene transfer of apoA-I[L218A/L219A/V221A/L222A] in apoA-I−/− mice decreased plasma cholesterol and apoA-I levels...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Panagiotis Fotakis, Andreas K. Kateifides, Christina Gkolfinopoulou, Dimitra Georgiadou, Melissa Beck, Katharina Gründler, Angeliki Chroni, Efstratios Stratikos, Dimitris Kardassis, Vassilis I. Zannis
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2013-12-01
श्रृंखला:	Journal of Lipid Research
विषय:	apolipoprotein A-I mutations pre-β and α-HDL particles dyslipidemia LCAT
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S0022227520356819
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