Alteration of negatively charged residues in the 89 to 99 domain of apoA-I affects lipid homeostasis and maturation of HDL[S]

Abstract In this study, we investigated the role of positively and negatively charged amino acids within the 89-99 region of apolipoprotein A-I (apoA-I), which are highly conserved in mammals, on plasma lipid homeostasis and the biogenesis of HDL. We previously showed that deletion of the 89-99 regi...

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Manylion Llyfryddiaeth

Prif Awduron:	Andreas K. Kateifides, Irina N. Gorshkova, Adelina Duka, Angeliki Chroni, Dimitris Kardassis, Vassilis I. Zannis
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Elsevier 2011-07-01
Cyfres:	Journal of Lipid Research
Pynciau:	apolipoprotein A-I mutations HDL biogenesis preβ and α-HDL particles dyslipidemia hypertriglyceridemia LCAT
Mynediad Ar-lein:	http://www.sciencedirect.com/science/article/pii/S0022227520370309
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