TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence
ABSTRACT Human telomerase reverse transcriptase (hTERT) plays a central role in telomere lengthening for continuous cell proliferation, but it remains unclear how extracellular cues regulate telomerase lengthening of telomeres. Here we report that the cytokine bone morphogenetic protein-7 (BMP7) ind...
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| Principais autores: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2016-09-01
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| Series: | Protein & Cell |
| Assuntos: | |
| Acceso en liña: | http://link.springer.com/article/10.1007/s13238-016-0322-1 |
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