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The positive inotropic effect of pyruvate involves an increase in myofilament calcium sensitivity.

Pyruvate is a metabolic fuel that is a potent inotropic agent. Despite its unique inotropic and antioxidant properties, the molecular mechanism of its inotropic mechanism is still largely unknown. To examine the inotropic effect of pyruvate in parallel with intracellular calcium handling under near...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Carlos A A Torres, Kenneth D Varian, Cynthia H Canan, Jonathan P Davis, Paul M L Janssen
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science (PLoS) 2013-01-01
Sarja:PLoS ONE
Linkit:http://europepmc.org/articles/PMC3655183?pdf=render
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