Hippocampal expression of murine TNFα results in attenuation of amyloid deposition in vivo

<p>Abstract</p> <p>Fibrillar amyloid β (fAβ) peptide is the major component of Aβ plaques in the brains of Alzheimer's disease (AD) patients. Inflammatory mediators have previously been proposed to be drivers of Aβ pathology in AD patients by increasing amyloidogenic processing of APP and promoting...

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Үндсэн зохиолчид:	Das Pritam, Ceballos-Diaz Carolina, Herring Amanda, Chakrabarty Paramita, Golde Todd E
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2011-02-01
Цуврал:	Molecular Neurodegeneration
Онлайн хандалт:	http://www.molecularneurodegeneration.com/content/6/1/16
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!