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Gene expression profiling and pathway analysis in head and neck squamous cell carcinoma: focus on disulfidptosis

Abstract This study aimed to characterize the prognostic and therapeutic implications of disulfidptosis-related genes (DRGs) in head and neck squamous cell carcinoma (HNSCC). Using multi-omics data from the Cancer Genome Atlas (TCGA) (n = 500) and Gene Expression Omnibus (GEO) cohorts (n = 270), we...

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Principais autores: Yajun Tong, Site Bai, Ludi Ou, Qiang Zhou, Songlian Liu, Leilan Yin, Kewei Tang, Ling Long, Qinghua Yin
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2025-04-01
Colecção:Discover Oncology
Assuntos:
Head and neck squamous cell carcinoma (HNSCC)
Disulfidptosis-related genes (DRGs)
Prognostic model
Immunotherapy response
Drug sensitivity
Acesso em linha:https://doi.org/10.1007/s12672-025-02344-2
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