Molecular characterization of non-muscle invasive tumor from N-methyl-N-nitrosourea (MNU)-induced urothelial carcinoma in a rat model reveals hallmarks of both luminal and basal subtypes

With the advances in molecular classification of bladder cancer subtypes, pre-clinical rodent models used to study urothelial tumorigenesis must be profiled to reflect clinical relevance and optimize translational research strategies. Murine models of bladder cancer such as the autochthonous N-butyl...

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Autors principals:	Kara A. Lombardo, Takahiro Yoshida, Evan Johnson, Kate Fitzgerald, Max Kates, William R. Bishai, Alex S. Baras, Trinity J. Bivalacqua
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2026-03-01
Col·lecció:	Experimental and Molecular Pathology
Matèries:	Bladder cancer N-methyl-N-nitrosourea (MNU) Molecular subtypes Immune infiltration Tumor progression Basal subtype
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S0014480026000110
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