Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge

The development of universal influenza vaccines has been a priority for more than 20 years. We conducted a preclinical study in ferrets of two sets of live attenuated influenza vaccines (LAIVs) expressing chimeric hemagglutinin (cHA). These vaccines contained the HA stalk domain from H1N1pdm09 virus...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Irina Isakova-Sivak, Victoria Matyushenko, Tatiana Kotomina, Irina Kiseleva, Elena Krutikova, Svetlana Donina, Andrey Rekstin, Natalia Larionova, Daria Mezhenskaya, Konstantin Sivak, Arman Muzhikyan, Anastasia Katelnikova, Larisa Rudenko
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2019-07-01
Цуврал:	Vaccines
Нөхцлүүд:	universal influenza vaccine chimeric hemagglutinin nucleoprotein live attenuated influenza vaccine sequential immunization ferret model
Онлайн хандалт:	https://www.mdpi.com/2076-393X/7/3/61
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!