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APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility

<p>Abstract</p> <p>Background</p> <p>It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understanding the function of proteins and studying their interactions. Experimental hot spots detection met...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Song Jiangning, Zhao Xing-Ming, Xia Jun-Feng, Huang De-Shuang
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2010-04-01
Rangatū:BMC Bioinformatics
Urunga tuihono:http://www.biomedcentral.com/1471-2105/11/174
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