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Spatial chemical conservation of hot spot interactions in protein-protein complexes

<p>Abstract</p> <p>Background</p> <p>Conservation of the spatial binding organizations at the level of physico-chemical interactions is important for the formation and stability of protein-protein complexes as well as protein and drug design. Due to the lack of computational tools for recognition of...

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Autori principali: Nussinov Ruth, Shatsky Maxim, Shulman-Peleg Alexandra, Wolfson Haim J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2007-10-01
Serie:BMC Biology
Accesso online:http://www.biomedcentral.com/1741-7007/5/43
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