<i>NSD1</i> Mutations and Pediatric High-Grade Gliomas: A Comparative Genomic Study in Primary and Recurrent Tumors

Pediatric high-grade gliomas represent a heterogeneous group of tumors with a wide variety of molecular features. We performed whole exome sequencing and methylation profiling on matched primary and recurrent tumors from four pediatric patients with hemispheric high-grade gliomas. Genetic analysis s...

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Autori principali:	Antonio d’Amati, Arianna Nicolussi, Evelina Miele, Angela Mastronuzzi, Sabrina Rossi, Francesca Gianno, Francesca Romana Buttarelli, Simone Minasi, Pietro Lodeserto, Marina Paola Gardiman, Elisabetta Viscardi, Anna Coppa, Vittoria Donofrio, Isabella Giovannoni, Felice Giangaspero, Manila Antonelli
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-12-01
Serie:	Diagnostics
Soggetti:	pediatric high-grade gliomas hemispheric pediatric high-grade gliomas high grade glioma H3-/IDH-wildtype glioma CNS tumors molecular biology
Accesso online:	https://www.mdpi.com/2075-4418/13/1/78
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