<i>NSD1</i> Mutations and Pediatric High-Grade Gliomas: A Comparative Genomic Study in Primary and Recurrent Tumors

Pediatric high-grade gliomas represent a heterogeneous group of tumors with a wide variety of molecular features. We performed whole exome sequencing and methylation profiling on matched primary and recurrent tumors from four pediatric patients with hemispheric high-grade gliomas. Genetic analysis s...

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Autors principals:	Antonio d’Amati, Arianna Nicolussi, Evelina Miele, Angela Mastronuzzi, Sabrina Rossi, Francesca Gianno, Francesca Romana Buttarelli, Simone Minasi, Pietro Lodeserto, Marina Paola Gardiman, Elisabetta Viscardi, Anna Coppa, Vittoria Donofrio, Isabella Giovannoni, Felice Giangaspero, Manila Antonelli
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2022-12-01
Col·lecció:	Diagnostics
Matèries:	pediatric high-grade gliomas hemispheric pediatric high-grade gliomas high grade glioma H3-/IDH-wildtype glioma CNS tumors molecular biology
Accés en línia:	https://www.mdpi.com/2075-4418/13/1/78
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