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Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials

Peptidoglycan (PG) is an essential macromolecular sacculus surrounding most bacteria. It is assembled by the glycosyltransferase (GT) and transpeptidase (TP) activities of multimodular penicillin-binding proteins (PBPs) within multiprotein complex machineries. Both activities are essential for the s...

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Bibliografische gegevens
Hoofdauteurs: Eric Sauvage, Mohammed Terrak
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2016-02-01
Reeks:Antibiotics
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Online toegang:http://www.mdpi.com/2079-6382/5/1/12
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