Glycosyltransferases and Transpeptidases/Penicillin-Binding Proteins: Valuable Targets for New Antibacterials

Peptidoglycan (PG) is an essential macromolecular sacculus surrounding most bacteria. It is assembled by the glycosyltransferase (GT) and transpeptidase (TP) activities of multimodular penicillin-binding proteins (PBPs) within multiprotein complex machineries. Both activities are essential for the s...

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Autors principals:	Eric Sauvage, Mohammed Terrak
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2016-02-01
Col·lecció:	Antibiotics
Matèries:	peptidoglycan glycosyltransferase transpeptidase penicillin-binding proteins β-lactam lipid II antibiotics resistance
Accés en línia:	http://www.mdpi.com/2079-6382/5/1/12
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