Carbamazepine-Mediated Adverse Drug Reactions: CBZ-10,11-epoxide but Not Carbamazepine Induces the Alteration of Peptides Presented by HLA-B∗15:02

Among patients treated with the anticonvulsive and psychotropic drug carbamazepine (CBZ), approximately 10% develop severe and life-threatening adverse drug reactions. These immunological conditions are resolved upon withdrawal of the medicament, suggesting that the drug does not manifest in the bod...

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Autors principals:	Gwendolin S. Simper, Gia-Gia T. Hò, Alexander A. Celik, Trevor Huyton, Joachim Kuhn, Heike Kunze-Schumacher, Rainer Blasczyk, Christina Bade-Döding
Format:	Artigo
Idioma:	Inglês
Publicat:	Wiley 2018-01-01
Col·lecció:	Journal of Immunology Research
Accés en línia:	http://dx.doi.org/10.1155/2018/5086503
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