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Influenza A virus NS1 suppresses nuclear speckles promoted gene expression by inhibition of transcription

Abstract IAV-NS1 proteins that interact with Cleavage and polyadenylation specific factor 30 are known to inhibit host gene expression. Here we report that in both transfection and infection experiments, a strong attenuation of reporter gene expression is observed when NS1 proteins are fused to prot...

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Autori principali: Wolfgang Nacken, Juliane Mayr, André Schreiber, Stephan Ludwig
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-05-01
Serie:npj Viruses
Accesso online:https://doi.org/10.1038/s44298-025-00124-x
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