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A systematic view on influenza induced host shutoff

Host shutoff is a common strategy used by viruses to repress cellular mRNA translation and concomitantly allow the efficient translation of viral mRNAs. Here we use RNA-sequencing and ribosome profiling to explore the mechanisms that are being utilized by the Influenza A virus (IAV) to induce host s...

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Principais autores: Adi Bercovich-Kinori, Julie Tai, Idit Anna Gelbart, Alina Shitrit, Shani Ben-Moshe, Yaron Drori, Shalev Itzkovitz, Michal Mandelboim, Noam Stern-Ginossar
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2016-08-01
Serier:eLife
Fag:
virus infection
host shutoff
translation
Online adgang:https://elifesciences.org/articles/18311
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