Identification of new benzofuran derivatives as STING agonists with broad-spectrum antiviral activity

The Stimulator of Interferon Genes (STING) is involved in cytosolic DNA sensing and type I Interferons (IFN-I) induction. Aiming to identify new STING agonists with antiviral activity and given the known biological activity of benzothiazole and benzimidazole derivatives, a series of benzofuran deriv...

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Autori principali:	A. Paulis, A. Onali, P.O. Vidalain, V. Lotteau, C. Jaquemin, A. Corona, S. Distinto, G.L. Delogu, E. Tramontano
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2024-09-01
Serie:	Virus Research
Soggetti:	STING Broad-spectrum antiviral Immune modulation Benzofurans Human coronaviruses
Accesso online:	http://www.sciencedirect.com/science/article/pii/S0168170224001254
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