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Synthesis of piperazine-based benzimidazole derivatives as potent urease inhibitors and molecular docking studies

Abstract The development of new bioactive compounds is important for progress in therapeutic research. In the present study, we describe the multistep synthetic approach to develop a library of novel benzimidazole analogs incorporating piperazine rings in order to increase their biological activity....

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Delaram Shahriarynejad, Navid Dastyafteh, Fouzia Naz, Meysam Talebi, Sajedeh Safapoor, Seyedeh Niloufar Ghafouri, Homa Azizian, Maryam Mohammadi-Khanaposhtani, Bagher Larijani, Mehdi Asadi, Massoud Amanlou, Mohammad Mahdavi, Khalid Mohammed Khan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2025-08-01
Sarja:Scientific Reports
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Linkit:https://doi.org/10.1038/s41598-025-14723-4
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