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Variability and longitudinal dynamics of donor-derived cell-free DNA in kidney and liver recipients: a comparison of absolute and relative quantities in plasma and urine

BackgroundDonor-derived cell-free DNA (ddcfDNA) is increasingly being integrated into clinical practice for detecting allograft rejection in solid organ recipients. Natural fluctuations in ddcfDNA or other conditions can affect interpretation. Therefore, we investigated ddcfDNA trends in kidney (KT)...

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Tallennettuna:
Päätekijät: Fanny Sandberg, Nicholas Kueng, Vanessa Banz, Annalisa Berzigotti, Daniel Sidler, Carlo R. Largiadèr, Ursula Amstutz
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2026-06-01
Sarja:Frontiers in Transplantation
Aiheet:
droplet digital PCR (ddPCR)
donor-derived cell-free DNA
kidney transplantation
liver transplantation
plasma
urine
Linkit:https://www.frontiersin.org/articles/10.3389/frtra.2026.1790754/full
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