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Investigation of Different Library Preparation and Tissue of Origin Deconvolution Methods for Urine and Plasma cfDNA Methylome Analysis

Methylation sequencing is a promising approach to infer the tissue of origin of cell-free DNA (cfDNA). In this study, a single- and a double-stranded library preparation approach were evaluated with respect to their technical biases when applied on cfDNA from plasma and urine. Additionally, tissue o...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Nicholas Kueng, Daniel Sidler, Vanessa Banz, Carlo R. Largiadèr, Charlotte K. Y. Ng, Ursula Amstutz
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2023-07-01
Rangatū:Diagnostics
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2075-4418/13/15/2505
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