The function of the conserved regulatory element within the second intron of the mammalian Csf1r locus.

The gene encoding the receptor for macrophage colony-stimulating factor (CSF-1R) is expressed exclusively in cells of the myeloid lineages as well as trophoblasts. A conserved element in the second intron, Fms-Intronic Regulatory Element (FIRE), is essential for macrophage-specific transcription of...

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Auteurs principaux:	Kristin A Sauter, M Amine Bouhlel, Julie O'Neal, David P Sester, Hiromi Tagoh, Richard M Ingram, Clare Pridans, Constanze Bonifer, David A Hume
Format:	Artigo
Langue:	Inglês
Publié:	Public Library of Science (PLoS) 2013-01-01
Collection:	PLoS ONE
Accès en ligne:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0054935&type=printable
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