Solubility of Sulfamethazine in Acetonitrile–Ethanol Cosolvent Mixtures: Thermodynamic Analysis and Mathematical Modeling

The low water solubility of sulfamethazine (SMT) limits its clinical efficacy, making it crucial to study techniques such as cosolvency to optimize pharmaceutical formulations. This study aimed to thermodynamically evaluate the solubility of SMT in {acetonitrile (MeCN) + ethanol (EtOH)} cosolvent mi...

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Detalhes bibliográficos

Principais autores:	Diego Ivan Caviedes-Rubio, Cristian Buendía-Atencio, Rossember Edén Cardenas-Torres, Claudia Patricia Ortiz, Fleming Martinez, Daniel Ricardo Delgado
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-09-01
coleção:	Molecules
Assuntos:	sulfamethazine cosolvent solubility Gibbs–van’t Hoff–Krug model
Acesso em linha:	https://www.mdpi.com/1420-3049/30/17/3590
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