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Thermodynamic Solubility Profile of Temozolomide in Different Commonly Used Pharmaceutical Solvents

The solubility parameters, and solution thermodynamics of temozolomide (TMZ) in 10 frequently used solvents were examined at five different temperatures. The maximum mole fraction solubility of TMZ was ascertained in dimethyl sulfoxide (1.35 × 10<sup>−2</sup>), followed by that in polyethylene glyco...

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Principais autores: Abdul Ahad, Faiyaz Shakeel, Mohammad Raish, Ajaz Ahmad, Yousef A. Bin Jardan, Fahad I. Al-Jenoobi, Abdullah M. Al-Mohizea
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2022-02-01
סדרה:Molecules
נושאים:
Apelblat and Van’t Hoff models
solubility
solution thermodynamics
temozolomide
גישה מקוונת:https://www.mdpi.com/1420-3049/27/4/1437
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