Analysis of high glucose injury using human induced pluripotent stem cell-derived kidney organoids

Abstract Background Diabetic kidney disease (DKD) is one of the most pervasive complications of diabetes worldwide. However, the pathogenesis of DKD remains poorly understood, due to limitations of the models. The hPSC-derived kidney organoids may offer a new possibility to solve the problem. Method...

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主要な著者:	Zuping Qian, Die Yang, Yongli Li, Rong Dong, Jingjing Da, Yong Chen, Yan Zha
フォーマット:	Artigo
言語:	Inglês
出版事項:	BMC 2026-01-01
シリーズ:	BMC Nephrology
主題:	Diabetic kidney disease (DKD) Kidney organoids Glucolipid metabolism Injury Apoptosis Inflammation
オンライン･アクセス:	https://doi.org/10.1186/s12882-025-04566-6
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